Ladostigil (hydrochloride) [CAS 209394-18-3]
Ladostigil (hydrochloride) [CAS 209394-18-3]
SKU:QM-0083522-01
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Product Details
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Description
Ladostigil (TV-3326) hydrochloride is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO), with IC50s of 37.1 and 31.8 μM for MAO-B and AChE, respectively. Ladostigil hydrochloride exhibits neuroprotective, antioxidant and anti-inflammatory activities. Ladostigil can be used for the research of depression and Alzheimer's disease[1][2]. Ladostigil (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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CAS Number
[209394-18-3]
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Molecular Formula
C16H21ClN2O2
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Molecular Weight
308.8
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Smiles
O=C(OC1=CC2=C(CC[C@H]2NCC#C)C=C1)N(CC)C.[H]Cl
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Target
Cholinesterase (ChE) ; Monoamine Oxidase
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Isoform
AChE; MAO-B
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Purity
99.91
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Ladostigil (hydrochloride) [CAS 209394-18-3]
Ladostigil (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.