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Laduviglusib (Standard) [CAS 252917-06-9]

Laduviglusib (Standard) [CAS 252917-06-9]

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SKU:QM-0081580-01

£263.84 GBP
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  • Description

    Laduviglusib (Standard) is the analytical standard of Laduviglusib. Laduviglusib (CHIR-99021) is a potent, selective and orally active GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib enhances mouse and human embryonic stem cells self-renewal. Laduviglusib induces autophagy[1][2][3].

  • CAS Number

    [252917-06-9]

  • Molecular Formula

    C22H18Cl2N8

  • Molecular Weight

    465.34

  • Smiles

    N#CC1=CC=C(N=C1)NCCNC2=NC=C(C(C3=CC=C(Cl)C=C3Cl)=N2)C4=NC=C(N4)C

  • Target

    Autophagy; GSK-3; Organoid; Reference Standards; Wnt; β-catenin

  • Purity

    99.52

  • Storage Conditions

    4°C, sealed storage, away from light and moisture

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H300, H312+H332, H315, H319, H335

  • Precautions

    H300, H312+H332, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0081580-01
5 mgQM-0081580-01
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10 mgQM-0081580-02
10 mgQM-0081580-02
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25 mgQM-0081580-03
25 mgQM-0081580-03
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50 mgQM-0081580-04
50 mgQM-0081580-04
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Laduviglusib (Standard) [CAS 252917-06-9]

Laduviglusib (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.