Lanabecestat (hydrochloride) [CAS 1383986-31-9]
Lanabecestat (hydrochloride) [CAS 1383986-31-9]
SKU:QM-0079641
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Product Details
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Description
Lanabecestat (AZD-3293) hydrochloride is a potent BACE1 inhibitor that has been investigated for its potential as a modifying treatment for Alzheimer's disease. Lanabecestat (hydrochloride) demonstrated significant dose- and time-dependent reductions in concentrations of amyloid beta peptides in plasma, cerebrospinal fluid, and brain. Lanabecestat (hydrochloride) was also shown to produce reductions in Aβ neuritic plaque burden without demonstrating clinical benefits or slowing the progression of Alzheimer's disease pathophysiology.
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CAS Number
[1383986-31-9]
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Molecular Formula
C26H29ClN4O
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Molecular Weight
448.99
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Smiles
CC#CC1=CC(C2=CC([C@@]34N=C(C)C(N)=N4)=C(C[C@@]53CC[C@@H](OC)CC5)C=C2)=CN=C1.Cl
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Target
Beta-secretase
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Shipping Conditions
Room temperature
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Lanabecestat (hydrochloride) [CAS 1383986-31-9]
Lanabecestat (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.