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Lapatinib (ditosylate monohydrate) [CAS 388082-78-8]

Lapatinib (ditosylate monohydrate) [CAS 388082-78-8]

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SKU:QM-0156506-01

£94.75 GBP
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  • Description

    Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].

  • CAS Number

    [388082-78-8]

  • Molecular Formula

    C43H44ClFN4O11S3

  • Molecular Weight

    943.48

  • Smiles

    O=S(CCNCC1=CC=C(C2=CC3=C(NC4=CC=C(OCC5=CC=CC(F)=C5)C(Cl)=C4)N=CN=C3C=C2)O1)(C)=O.O=S(C6=CC=C(C)C=C6)(O)=O.O=S(C7=CC=C(C)C=C7)(O)=O.O

  • Target

    Autophagy; EGFR; Ferroptosis

  • Isoform

    EGFR/ErbB1/HER1; ErbB2/HER2

  • Concentration

    10mM

  • Purity

    99.99

  • Solubility

    DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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50 mgQM-0156506-01
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10 mM - 1 mLQM-0156506-02
10 mM - 1 mLQM-0156506-02
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100 mgQM-0156506-03
100 mgQM-0156506-03
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Lapatinib (ditosylate monohydrate) [CAS 388082-78-8]

Lapatinib (ditosylate monohydrate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.