Lazabemide (hydrochloride) [CAS 103878-83-7]
Lazabemide (hydrochloride) [CAS 103878-83-7]
SKU:QM-0064926-01
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Product Details
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Description
Lazabemide hydrochloride (Ro 19-6327 hydrochloride) is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM) but less active for MAO-A (IC50>100 μM) . Lazabemide inhibits monoamine uptake at high concentrations, the IC50 values are 86 μM, 123 μM and >500 μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease[1].
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CAS Number
[103878-83-7]
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Molecular Formula
C8H11Cl2N3O
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Molecular Weight
236.1
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Smiles
O=C(C1=NC=C(Cl)C=C1)NCCN.[H]Cl
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Target
Monoamine Oxidase
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Isoform
MAO-B
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H315-H319-H335
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Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
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Lazabemide (hydrochloride) [CAS 103878-83-7]
Lazabemide (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.