Lazertinib (mesylate) [CAS 2247995-37-3]
Lazertinib (mesylate) [CAS 2247995-37-3]
SKU:QM-0003524-01
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Product Details
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Description
Lazertinib (mesylate) (YH25448 (mesylate) ; GNS-1480 (mesylate) ) is an orally active EGFR inhibitor that can penetrate the blood-brain barrier. Lazertinib (mesylate) inhibits p-EGFR, p-AKT and p-ERK signaling pathways, leading to apoptosis. Lazertinib (mesylate) has anti-tumor activity in the mouse H1975-luc BM xenograft model. Lazertinib (mesylate) can be used in the study of non-small cell lung cancer[1].
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CAS Number
[2247995-37-3]
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Molecular Formula
C31H38N8O6S
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Molecular Weight
650.75
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Smiles
O=C(NC1=CC(NC2=NC=CC(N3N=C(C(CN(C)C)=C3)C4=CC=CC=C4)=N2)=C(C=C1N5CCOCC5)OC)C=C.O=S(O)(C)=O
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Target
Akt; EGFR; ERK
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Purity
99.85
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Lazertinib (mesylate) [CAS 2247995-37-3]
Lazertinib (mesylate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.