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LDHA-IN-8
LDHA-IN-8
SKU:QM-0135308
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Quantity
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Product Details
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Description
LDHA-IN-8 (Compound 6) is a lactate dehydrogenase (LDHA) inhibitor. LDHA-IN-8 inhibits LDHA catalysis of pyruvate in a dose-dependent manner (EC50 value of 14.54 μM), reduces intracellular lactate levels, and increases intracellular reactive oxygen species (ROS) levels, thereby inhibiting the proliferation of pancreatic cancer cells and lung cancer cells. LDHA-IN-8 holds promise for research in the field of LDHA-related antitumor therapies[1].
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Molecular Formula
C15H14N4O2
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Molecular Weight
282.3
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Smiles
CC1=CC(/C=C2C(NC(N/2)=O)=O)=C(C)N1C3=CN=CC=C3
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Target
Lactate Dehydrogenase
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Isoform
LDHA
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Shipping Conditions
Room temperature
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LDHA-IN-8
LDHA-IN-8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.