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LDN193189 (Tetrahydrochloride) [CAS 2310134-98-4]
LDN193189 (Tetrahydrochloride) [CAS 2310134-98-4]
SKU:QM-0004654-01
£122.88 GBP
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Product Details
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Description
LDN193189 Tetrahydrochloride is a selective BMP type I receptor inhibitor, which efficiently inhibits ALK2 and ALK3 (IC50=5 nM and 30 nM, respectively), with weaker effects on ALK4, ALK5 and ALK7 (IC50≥500 nM) [1].
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CAS Number
[2310134-98-4]
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Molecular Formula
C25H26Cl4N6
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Molecular Weight
552.33
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Smiles
C1(C2=C3N=CC(C4=CC=C(N5CCNCC5)C=C4)=CN3N=C2)=CC=NC6=CC=CC=C16.Cl.Cl.Cl.Cl
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Target
Organoid; TGF-β Receptor
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Isoform
ALK2; ALK3
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Purity
99.79
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Solubility
DMSO : 4.17 mg/mL (ultrasonic) |H2O : 33.33 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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LDN193189 (Tetrahydrochloride) [CAS 2310134-98-4]
LDN193189 (Tetrahydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.