Lenalidomide-propargyl-C2-NH2 (hydrochloride) [CAS 2489242-23-9]
Lenalidomide-propargyl-C2-NH2 (hydrochloride) [CAS 2489242-23-9]
SKU:QM-0076779-01
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Product Details
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Description
Lenalidomide-propargyl-C2-NH2 hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Lenalidomide-propargyl-C2-NH2 hydrochloride can be used to design the PROTAC MD-224. Lenalidomide-propargyl-C2-NH2 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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CAS Number
[2489242-23-9]
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Molecular Formula
C18H20ClN3O3
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Molecular Weight
361.82
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Smiles
O=C(C(N(CC1=C2C=CC=C1C#CCCCN)C2=O)CC3)NC3=O.Cl
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Target
E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Purity
98.04
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Solubility
10 mM in DMSO
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lenalidomide-propargyl-C2-NH2 (hydrochloride) [CAS 2489242-23-9]
Lenalidomide-propargyl-C2-NH2 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.