Leukotriene B5 [CAS 80445-66-5]
Leukotriene B5 [CAS 80445-66-5]
SKU:QM-0134218-01
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Product Details
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Description
Leukotriene B5 (LTB5) is a leukotriene with diverse biological activities. It is a metabolite of eicosapentaenoic acid formed through the 5-lipoxygenase (5-LO) pathway. LTB5 increases contraction of bullfrog lung strips ex vivo in a concentration-dependent manner. In vivo, LTB5 (100 nM) reduces tumor volume in mice injected with Tm1 murine melanoma cells. LTB5 also elicits chemokinesis and lysosomal enzyme release from polymorphonuclear leukocytes (PMNLs) 20- to 30-fold less, and induces platelet aggregation 8-fold less, potently than LTB4.
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CAS Number
[80445-66-5]
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Molecular Formula
C20H30O4
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Molecular Weight
334.45
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Smiles
CC/C=C\C/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(O)=O
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Target
Leukotriene Receptor
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Shipping Conditions
Room temperature
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Hazard Statement
H315-H319-H335
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Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
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Leukotriene B5 [CAS 80445-66-5]
Leukotriene B5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.