Levocabastine (hydrochloride) [CAS 79547-78-7]
Levocabastine (hydrochloride) [CAS 79547-78-7]
SKU:QM-0147842-01
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Product Details
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Description
Levocabastine (R 50547) hydrochloride is a potent and selective histamine H1-receptor antagonist. Levocabastine hydrochloride is also a selective, high affinity neurotensin receptor subtype 2 (NTR2) antagonist, with a Ki of 17 nM for mNTR2. Levocabastine hydrochloride can act as a VLA-4 antagonist, interferes with conjunctival eosinophil infiltration in allergic conjunctivitis (AC) [1][2][3].
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CAS Number
[79547-78-7]
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Molecular Formula
C26H30ClFN2O2
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Molecular Weight
456.98
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Smiles
OC([C@@]1(C2=CC=CC=C2)[C@@H](CN([C@]3([H])CC[C@](CC3)(C4=CC=C(C=C4)F)C#N)CC1)C)=O.[H]Cl
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Target
Histamine Receptor; Integrin; Neurotensin Receptor
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Isoform
H1 Receptor; NTR2
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Purity
99.3
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Hazard Statement
H315, H319, H335
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Precautions
H315, H319, H335
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Levocabastine (hydrochloride) [CAS 79547-78-7]
Levocabastine (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.