Lipopolysaccharides, from E. coli O55:B5
Lipopolysaccharides, from E. coli O55:B5
SKU:QM-0160897-01
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Product Details
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Description
Lipopolysaccharides, from E. coli O55:B5 (LPS, from Escherichia coli (O55:B5) ) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O55:B5) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O55:B5 possess the typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O55:B5 activate TLR-4 in immune cells, exhibit high pyrogenicity, and demonstrate dose and serotype specificity. Lipopolysaccharides, from E. coli O55:B5 can be widely used to induce cellular inflammation and establish animal models related to inflammation[1][2][3][4][5][6][7]. It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
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Smiles
[Lipopolysaccharides,fromE.coliO55:B5]
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Target
Toll-like Receptor (TLR)
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Isoform
TLR4
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Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 5 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Lipopolysaccharides, from E. coli O55:B5
Lipopolysaccharides, from E. coli O55:B5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.