Lipopolysaccharides, from S. marcescens
Lipopolysaccharides, from S. marcescens
SKU:QM-0088690
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Product Details
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Description
Lipopolysaccharides, from S. marcescens (Serratia marcescens) are lipopolysaccharide endotoxins and TLR-4 activators derived from Serratia marcescens, classified as S-type LPS, which can activate pathogen-associated molecular patterns (PAMP) of the immune system and induce cellular secretion of migrasomes. Lipopolysaccharides, from S. marcescens exhibit a typical three-part structure: O-antigen (O-antigen), core oligosaccharide (core oligosaccharide), and lipid A (Lipid A) . Lipopolysaccharides, from S. marcescens induce NF-κB activation in mouse cells via Toll-like receptor (TLR4) /MD-2. The lipopolysaccharides of S. marcescens can induce apoptosis in host immune cells, thereby suppressing the host's innate immunity[1][2]. It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
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Smiles
[Lipopolysaccharides,fromS.marcescens]
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Target
Toll-like Receptor (TLR)
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Solubility
H2O : 5 mg/mL (ultrasonic; warming)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Lipopolysaccharides, from S. marcescens
Lipopolysaccharides, from S. marcescens is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.