Lithocholic amide-C2-N (didecane) [CAS 2768690-22-6]
Lithocholic amide-C2-N (didecane) [CAS 2768690-22-6]
SKU:QM-0015466
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Product Details
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Description
Lithocholic amide-C2-N (didecane) (Compound LC10) is a Lithocholic acid analogue. Lithocholic amide-C2-N (didecane) can form lipid nanoparticles spontaneously in the aqueous milieu, permeate through the skin, penetrate the deeper dermal layers, and exert anti-inflammatory effects against psoriasis-like chronic skin inflammations. Lithocholic amide-C2-N (didecane) can inhibit abnormal proliferation of keratinocytes, downregulate the mRNA expression of the psoriasis-associated receptor EphA2 and reduce serum levels of multiple pro-inflammatory factors such as IL-1α, IL-1β, and IFN-γ by inhibiting activation of the Th17/Th2 inflammatory pathway[1].
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CAS Number
[2768690-22-6]
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Molecular Formula
C46H86N2O2
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Molecular Weight
699.19
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Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCCN(CCCCCCCCCC)CCCCCCCCCC)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])CC3)C
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Target
Drug Derivative; Ephrin Receptor; IFNAR; Interleukin Related
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Isoform
EphA; IL-1
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Shipping Conditions
Room temperature
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Lithocholic amide-C2-N (didecane) [CAS 2768690-22-6]
Lithocholic amide-C2-N (didecane) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.