Lixisenatide (Leu-13C6,15N) (TFA)
Lixisenatide (Leu-13C6,15N) (TFA)
SKU:QM-0024919
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Product Details
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Description
Lixisenatide (Leu-13C6,15N) TFA is the 13C- and 15N-labeled Lixisenatide. Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist. Lixisenatide inhibits the inflammatory response through down regulation of pro-inflammatory cytokines, and suppresses of the Akt-MEK1/2 signaling pathway. Lixisenatide can inhibit oxidative stress, mitochondrial dysfunction and apoptosis. Lixisenatide can be used for the researches of inflammation, metabolic disease, neurological disease and cardiovascular disease, such as rheumatoid arthritis, diabetes, Alzheimer's disease and atherosclerosis[1][2][3][4][5][6].
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Molecular Formula
C210 13C6H349N60 15NO65S.xC2HF3O2
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Smiles
C[15N](C([C@H](CC(O)=O)NC([C@H](CO)NC([C@H]([C@@H](C)O)NC([C@H](CC1=CC=CC=C1)NC([C@H]([C@@H](C)O)NC(CNC([C@H](CCC(O)=O)NC(CNC([C@@H](N)CC2=CNC=N2)=O)=O)=O)=O)=O)=O)=O)=O)=O)[13C@H]([13C](N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N3[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N4[C@H](C(N5[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CCCCN)=O)CCCCN)=O)CCCCN)=O)CCCCN)=O)CCCCN)=O)CO)=O)CCC5)=O)CCC4)=O)C)=O)=O)CO)=O)CO)=O)CCC3)=O)=O)=O)CC(N)=O)=O)CCCCN)=O)CC(C)C)=O)CC6=CNC7=CC=CC=C67)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CC8=CC=CC=C8)=O)CC(C)C)=O)CCCNC(N)=N)=O)C(C)C)=O)C)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCSC)=O)CCC(N)=O)=O)CCCCN)=O)CO)=O)[13CH2][13CH]([13CH3])[13CH3].O=C(O)C(F)(F)F.[x]
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Target
Akt; Apoptosis; GLP Receptor; Isotope-Labeled Compounds; MEK; MMP; Reactive Oxygen Species (ROS)
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Isoform
MEK1; MMP-1; MMP-13; MMP-2; MMP-3
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Shipping Conditions
Room temperature
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Lixisenatide (Leu-13C6,15N) (TFA)
Lixisenatide (Leu-13C6,15N) (TFA) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.