Lorukafusp alfa [CAS 2131168-99-3]
Lorukafusp alfa [CAS 2131168-99-3]
SKU:QM-0122404-01
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Product Details
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Description
Lorukafusp alfa (14.18 mAb; hu14.18-IL2) is an immunocytokine consisting of the humanized 14.18 anti-GD2 mAb linked to IL210. Lorukafusp alfa has activity mediated by activation of antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity via the binding of hu14.18-IL2 to GD2 on the tumor cell surface, followed by binding to Fc receptors on effector cells along with activation of NK and T cells via IL2 receptor binding. Lorukafusp alfa has anti-tumor activity[1].
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CAS Number
[2131168-99-3]
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Smiles
[Lorukafuspalfa]
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Target
Others
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Purity
97.8
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Solubility
10 mM in DMSO
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Storage Conditions
Store at -80°C for 2 years
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Shipping Conditions
Dry Ice
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Lorukafusp alfa [CAS 2131168-99-3]
Lorukafusp alfa is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.