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LXE408 (fumarate) [CAS 3026790-19-9]
LXE408 (fumarate) [CAS 3026790-19-9]
SKU:QM-0005721
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Product Details
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Description
LXE408 fumarate is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. LXE408 fumarate has an IC50 of 0.04 μM for L. donovani proteasome and an EC50 of 0.04 μM for L. donovani. LXE408 fumarate has a low propensity to cross the blood brain barrier. LXE408 fumarate has the potential for visceral leishmaniasis (VL) research[1].
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CAS Number
[3026790-19-9]
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Molecular Formula
C27H22FN7O6
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Molecular Weight
559.51
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Smiles
O=C(C1=C(C)N=C(C)O1)NC2=CC=C(F)C(C3=NN4C=C(C5=NC=CC=C5C)C=NC4=N3)=C2.O=C(O)/C=C/C(O)=O
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Target
Parasite; Proteasome
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Shipping Conditions
Room temperature
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LXE408 (fumarate) [CAS 3026790-19-9]
LXE408 (fumarate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.