LY367385 (hydrochloride) [CAS 2829282-00-8]
LY367385 (hydrochloride) [CAS 2829282-00-8]
SKU:QM-0112564-01
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Product Details
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Description
LY367385 hydrochloride is a highly selective and potent mGluR1a antagonist. LY367385 hydrochloride has an IC50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 hydrochloride has neuroprotective, anticonvulsant and antiepileptic effects[1][2].
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CAS Number
[2829282-00-8]
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Molecular Formula
C10H12ClNO4
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Molecular Weight
245.66
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Smiles
OC([C@H](C1=C(C=C(C(O)=O)C=C1)C)N)=O.[H]Cl
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Target
MGluR
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Isoform
MGluR1
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Purity
99.47
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Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 12.5 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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LY367385 (hydrochloride) [CAS 2829282-00-8]
LY367385 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.