M-Chlorophenylbiguanide [CAS 48144-44-1]
M-Chlorophenylbiguanide [CAS 48144-44-1]
SKU:QM-0102885
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Product Details
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Description
M-Chlorophenylbiguanide (mCPBG) is a potent high-affinity agonist of the 5-HT3 receptor, exhibiting an inhibitory effect on long-term potentiation (LTP) in the mossy fiber-CA3 system. mCPBG attenuates the magnitude of LTP at concentrations of 0.3-1 microM, demonstrating its role in modulating synaptic plasticity. Additionally, the impact of mCPBG on LTP is reversible by the GABAA receptor antagonist bicuculline, indicating a connection between its action and GABAergic neurotransmission.
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CAS Number
[48144-44-1]
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Molecular Formula
C8H10ClN5
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Molecular Weight
211.65
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Smiles
N=C(NC1=CC=CC(Cl)=C1)NC(N)=N
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Target
5-HT Receptor
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Purity
90
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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M-Chlorophenylbiguanide [CAS 48144-44-1]
M-Chlorophenylbiguanide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.