Malvidin-3-glucoside (chloride) [CAS 7228-78-6]
Malvidin-3-glucoside (chloride) [CAS 7228-78-6]
SKU:QM-0141583-01
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Product Details
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Description
Malvidin-3-glucoside (Malvidin-3-O-glucoside; Oenin) chloride is an orally active inhibitor of the NF-κB pathway, which blocks inflammatory responses induced by TNF-α, reduces IκB-α degradation and p65 nuclear translocation, and upregulates endothelial nitric oxide synthase eNOS to increase NO production. Malvidin-3-glucoside chloride exerts anti-inflammatory and antioxidant effects by inhibiting pro-inflammatory molecules such as MCP-1, ICAM-1, and IL-6, and regulating intestinal microorganisms and metabolites, while protecting endothelial cells and improving intestinal microecological dysbiosis under inflammatory conditions. Malvidin-3-glucoside chloride can be used to study chronic inflammatory-related diseases such as atherosclerosis and inflammatory bowel disease, and has the potential to prevent vascular inflammation and improve intestinal health[1][2][3].
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CAS Number
[7228-78-6]
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Molecular Formula
C23H25ClO12
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Molecular Weight
528.89
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Smiles
OC1=CC2=C(C=C(C(C3=CC(OC)=C(C(OC)=C3)O)=[O+]2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)C(O)=C1.[Cl-]
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Target
Interleukin Related; NF-κB; NO Synthase; TNF Receptor
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Isoform
ENOS; IL-6
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Purity
99.87
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Solubility
DMSO : 25 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Malvidin-3-glucoside (chloride) [CAS 7228-78-6]
Malvidin-3-glucoside (chloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.