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Manidipine (dihydrochloride) (Standard) [CAS 89226-75-5]

Manidipine (dihydrochloride) (Standard) [CAS 89226-75-5]

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SKU:QM-0011725-01

£57.09 GBP
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  • Description

    Manidipine (dihydrochloride) (Standard) is the analytical standard of Manidipine (dihydrochloride) . This product is intended for research and analytical applications. Manidipine dihydrochloride is a third-generation, lipophilic, orally active and highly vasoselective calcium channel antagonist (IC50 = 2.6 nM in guinea-pig ventricular cells) and acts as an antihypertensive agent. Manidipine effectively reduces blood pressure as well as improving insulin sensitivity, renal protection, and antiatherosclerotic activity. Manidipine also exerts anti-inflammatory activity mediated by NF-κB and antiviral activity against many flavivirus and negative-strand RNA viruses through the inhibition of calcium channel. Manidipine is widely applied to research of cardiovascular, metabolic disease and infection[1][2][3][4][5][6].

  • CAS Number

    [89226-75-5]

  • Molecular Formula

    C35H40Cl2N4O6

  • Molecular Weight

    683.62

  • Smiles

    O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OCCN3CCN(C(C4=CC=CC=C4)C5=CC=CC=C5)CC3.[H]Cl.[H]Cl

  • Target

    Calcium Channel; NF-κB; Reference Standards

  • Shipping Conditions

    Room temperature

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Variant Variant total Quantity Price Variant total
5 mgQM-0011725-01
5 mgQM-0011725-01
£57.09/ea
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10 mgQM-0011725-02
10 mgQM-0011725-02
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25 mgQM-0011725-03
25 mgQM-0011725-03
£115.00/ea
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50 mgQM-0011725-04
50 mgQM-0011725-04
£195.80/ea
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100 mgQM-0011725-05
100 mgQM-0011725-05
£268.70/ea
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Manidipine (dihydrochloride) (Standard) [CAS 89226-75-5]

Manidipine (dihydrochloride) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.