Mavorixafor (trihydrochloride) [CAS 2309699-17-8]
Mavorixafor (trihydrochloride) [CAS 2309699-17-8]
SKU:QM-0156395-01
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Product Details
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Description
Mavorixafor trihydrochloride (AMD-070 trihydrochloride) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively.Mavorixafor trihydrochloride can be used for the study of WHIM syndrome[1].
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CAS Number
[2309699-17-8]
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Molecular Formula
C21H30Cl3N5
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Molecular Weight
458.86
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Smiles
[H]Cl.[H]Cl.[H]Cl.NCCCCN(CC1=NC2=CC=CC=C2N1)[C@@H]3C4=NC=CC=C4CCC3
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Target
CXCR; HIV
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Isoform
CXCR4; HIV-1
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Concentration
10mM
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Purity
99.75
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Solubility
DMSO : 150 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Mavorixafor (trihydrochloride) [CAS 2309699-17-8]
Mavorixafor (trihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.