MBM-55 (Standard) [CAS 2083622-09-5]
MBM-55 (Standard) [CAS 2083622-09-5]
SKU:QM-0002152
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Product Details
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Description
MBM-55 (Standard) is the analytical standard of MBM-55. This product is intended for research and analytical applications. MBM-55 is a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 1 nM. MBM-55 shows a 20-fold or greater selectivity in most kinases with the exception of RSK1 (IC50=5.4 nM) and DYRK1a (IC50=6.5 nM). MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-55 shows antitumor activities, and no obvious toxicity to mice[1].
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CAS Number
[2083622-09-5]
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Molecular Formula
C28H27FN6O2
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Molecular Weight
498.55
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Smiles
NC(C(C=C1)=C(OCC2=CC=CC(F)=C2)C=C1C3=CN=C4N3C=CC(C5=CN(CCN(C)C)N=C5)=C4)=O
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Target
Apoptosis; NEKs; Reference Standards
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Shipping Conditions
Room temperature
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MBM-55 (Standard) [CAS 2083622-09-5]
MBM-55 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.