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MEK-IN-7 [CAS 2256822-22-5]
MEK-IN-7 [CAS 2256822-22-5]
SKU:QM-0014882
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Product Details
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Description
MEK-IN-7 (compound WX086) is potent, orally active and selective MEK inhibitor (MEK1 IC50 = 29.62 nM) . MEK-IN-7 inhibits HT29 and A375 cell proliferation with IC50s of 0.62 and 0.40 nM. MEK-IN-7 inhibits tumor growth in a HL-29 xenograft mouse model. MEK-IN-7 can be used for melanoma and colon cancer research[1].
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CAS Number
[2256822-22-5]
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Molecular Formula
C27H25FIN3O5S
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Molecular Weight
649.47
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Smiles
O=C1OC2=C(C(NC3=CC=C(C=C3F)I)=C1C)C(N(C4CC4)C(C)=C2C5=C(C)C(NS(C)(=O)=O)=CC=C5)=O
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Target
MEK
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Isoform
MEK1
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Shipping Conditions
Room temperature
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MEK-IN-7 [CAS 2256822-22-5]
MEK-IN-7 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.