Methazolamide [CAS 554-57-4]
Methazolamide [CAS 554-57-4]
SKU:QM-0158581-01
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Product Details
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Description
Methazolamide (L584601) is a BBB-penetrable and orally active carbonic anhydrase inhibitor, with a Ki of 14 nM for human carbonic anhydrase II. Methazolamide can reduce intraocular pressure and has a neuroprotective effect, being able to inhibit neuronal apoptosis. Methazolamide can be used in the research of ophthalmic diseases such as glaucoma and cerebrovascular diseases such as subarachnoid hemorrhage[1][2][3].
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CAS Number
[554-57-4]
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Molecular Formula
C5H8N4O3S2
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Molecular Weight
236.27
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Smiles
CC(/N=C1SC(S(=O)(N)=O)=NN/1C)=O
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Target
Apoptosis; Carbonic Anhydrase; Caspase; Reactive Oxygen Species (ROS)
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Isoform
CA II
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Purity
99.43
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Solubility
DMSO : ≥ 50 mg/mL
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Methazolamide [CAS 554-57-4]
Methazolamide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.