Methyl-L-NIO (hydrochloride) [CAS 150403-96-6]
Methyl-L-NIO (hydrochloride) [CAS 150403-96-6]
SKU:QM-0087902-01
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Product Details
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Description
Methyl-L-NIO (compound 2d) hydrochloride is a potential selective inhibitor (IC50: 70 μM) of dimethylarginine dimethylaminohydrolase hDDAH. Methyl-L-NIO also has inhibitory activity against NO synthase. The inhibition rates of Methyl-L-NIO on different isoforms of NO synthase at a concentration of 100 μM are 77% (nNOS), 20% (eNOS), and 72% (iNOS) respectively; the inhibition rates at a concentration of 1 mM are 100% (nNOS), 85% (eNOS), 100% (iNOS) [1].
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CAS Number
[150403-96-6]
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Molecular Formula
C8H18ClN3O2
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Molecular Weight
223.7
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Smiles
N[C@@H](CCCNC(CC)=N)C(O)=O.Cl
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Target
NO Synthase
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Shipping Conditions
Room temperature
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Hazard Statement
H315-H319-H335
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Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
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Methyl-L-NIO (hydrochloride) [CAS 150403-96-6]
Methyl-L-NIO (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.