Migalastat (hydrochloride) -15N [CAS 1219134-37-8]
Migalastat (hydrochloride) -15N [CAS 1219134-37-8]
SKU:QM-0053588-01
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Product Details
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Description
Migalastat hydrochloride-15N (GR181413A-15N) is the 15N-labeled Migalastat hydrochloride. Migalastat (GR181413A free base) hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity[1].
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CAS Number
[1219134-37-8]
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Molecular Formula
C6H14Cl 15NO4
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Molecular Weight
200.63
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Smiles
O[C@H]1[C@H]([C@H]([15NH]C[C@@H]1O)CO)O.Cl
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Target
Glycosidase; Isotope-Labeled Compounds
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Shipping Conditions
Room temperature
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Migalastat (hydrochloride) -15N [CAS 1219134-37-8]
Migalastat (hydrochloride) -15N is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.