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Milameline (hydroiodide)

Milameline (hydroiodide)

Size

QM-0112662-01

£135.25 GBP
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Product Details

  • Description

    Milameline (CI 979; RU35926) hydroiodide is a nonselective, partical and orally active muscarinic receptor agonist that improves cognition. Milameline hydroiodide has equal affinity for different subtypes of human muscarinic receptors with IC50 of 1.3 µM for M1-, 1.1 µM for M2-, 1.5 µM for M3-, and 1.9 µM for M4-muscarinic receptors. Milameline hydroiodide has a higher affinity for sites [3H]CMD (IC50 = 20 nM), than [3H]QNB, (IC50 = 3059 nM). Milameline hydroiodide produces both central and peripheral cholinergic effects and reverses the cognitive deficits induced by Scopolamine. Milameline hydroiodide can be used for the study of Alzheimer’s Disease[1].

  • Molecular Formula

    C8H15IN2O

  • Molecular Weight

    282.12

  • Smiles

    CO/N=C/C1=CCCN(C)C1.I

  • Target

    MAChR

  • Isoform

    MAChR1; mAChR2; mAChR3; mAChR4

  • Purity

    96.25

  • Storage Conditions

    -20°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Blue Ice
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Variant Variant total Quantity Price Variant total
5 mgQM-0112662-01
5 mgQM-0112662-01
£88.20
£135.25/ea
 £0.00
£88.20
£135.25/ea
 £0.00
10 mgQM-0112662-02
10 mgQM-0112662-02
£139.50
£238.32/ea
 £0.00
£139.50
£238.32/ea
 £0.00
25 mgQM-0112662-03
25 mgQM-0112662-03
£283.50
£432.73/ea
 £0.00
£283.50
£432.73/ea
 £0.00
50 mgQM-0112662-04
50 mgQM-0112662-04
£455.40
£664.79/ea
 £0.00
£455.40
£664.79/ea
 £0.00
100 mgQM-0112662-05
100 mgQM-0112662-05
£725.40
£1,029.29/ea
 £0.00
£725.40
£1,029.29/ea
 £0.00
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Milameline (hydroiodide)

Milameline (hydroiodide) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.