Miransertib (hydrochloride) [CAS 1313883-00-9]
Miransertib (hydrochloride) [CAS 1313883-00-9]
SKU:QM-0155481-01
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Product Details
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Description
Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. Miransertib hydrochloride is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research[1]. Miransertib hydrochloride is effective against Leishmania[2].
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CAS Number
[1313883-00-9]
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Molecular Formula
C27H25ClN6
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Molecular Weight
468.98
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Smiles
NC1=NC=CC=C1C2=NC3=CC=C(C4=CC=CC=C4)N=C3N2C5=CC=C(C6(N)CCC6)C=C5.[H]Cl
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Target
Akt; Parasite
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Isoform
Akt1; Akt2; Akt3; Leishmania
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Purity
99.74
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Solubility
DMSO : 50 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H319, H320
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Precautions
H315, H319, H320
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Miransertib (hydrochloride) [CAS 1313883-00-9]
Miransertib (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.