Mitapivat (hydrochloride) [CAS 2559738-69-9]
Mitapivat (hydrochloride) [CAS 2559738-69-9]
SKU:QM-0005333
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Product Details
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Description
Mitapivat (AG-348) hydrochloride is an orally active and selective allosteric pyruvate kinase R (PK-R) activator. Mitapivat hydrochloride accelerates the reaction of PK-R catalyzing the conversion of phosphoenolpyruvate to pyruvate, thereby promoting the glycolytic pathway, increasing the production of adenosine triphosphate (ATP) in red blood cells, and reducing the level of 2,3-diphosphoglycerate (2,3-DPG) . Mitapivat hydrochloride is promising for research of pyruvate kinase deficiency and other anemia-related diseases[1].
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CAS Number
[2559738-69-9]
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Molecular Formula
C24H27ClN4O3S
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Molecular Weight
487.01
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Smiles
O=S(C1=C2N=CC=CC2=CC=C1)(NC3=CC=C(C(N4CCN(CC5CC5)CC4)=O)C=C3)=O.[H]Cl
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Target
Pyruvate Kinase
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Shipping Conditions
Room temperature
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Mitapivat (hydrochloride) [CAS 2559738-69-9]
Mitapivat (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.