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Mitoguazone (Standard) [CAS 459-86-9]

Mitoguazone (Standard) [CAS 459-86-9]

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SKU:QM-0112239

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  • Description

    Mitoguazone (Standard) is the analytical standard of Mitoguazone. This product is intended for research and analytical applications. Mitoguazone (Methylglyoxal-bis (guanylhydrazone) ) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment[1][2][3][4].

  • CAS Number

    [459-86-9]

  • Molecular Formula

    C5H12N8

  • Molecular Weight

    184.2

  • Smiles

    CC(/C=N/NC(N)=N)=N\NC(N)=N

  • Target

    Apoptosis; HIV; Reference Standards

  • Shipping Conditions

    Room temperature

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Mitoguazone (Standard) [CAS 459-86-9]

Mitoguazone (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.