Mitotane-13C12 [CAS 2483736-36-1]
Mitotane-13C12 [CAS 2483736-36-1]
SKU:QM-0080172
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Product Details
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Description
Mitotane-13C12 (2,4′-DDD-13C12) is 13C labeled Mitotane. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions[1][2][3][4][1][2][3][4][5].
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CAS Number
[2483736-36-1]
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Molecular Formula
C2 13C12H10Cl4
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Molecular Weight
331.95
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Smiles
ClC(Cl)C([13C]1=[13CH][13CH]=[13C]([13CH]=[13CH]1)Cl)[13C]2=[13C]([13CH]=[13CH][13CH]=[13CH]2)Cl
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Target
Apoptosis; Isotope-Labeled Compounds
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Shipping Conditions
Room temperature
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Mitotane-13C12 [CAS 2483736-36-1]
Mitotane-13C12 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.