Mitotane-13C6 [CAS 1261396-21-7]
Mitotane-13C6 [CAS 1261396-21-7]
SKU:QM-0063113
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Product Details
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Description
Mitotane-13C6 is the 13C labeled Mitotane[1]. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions[2][3][4][5].
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CAS Number
[1261396-21-7]
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Molecular Formula
C8 13C6H10Cl4
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Molecular Weight
326
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Smiles
ClC(Cl)C([13C]1=[13CH][13CH]=[13C]([13CH]=[13CH]1)Cl)C2=C(C=CC=C2)Cl
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Target
Apoptosis
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Purity
98.62
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Mitotane-13C6 [CAS 1261396-21-7]
Mitotane-13C6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.