MK-8033 (hydrochloride) [CAS 1283000-43-0]
MK-8033 (hydrochloride) [CAS 1283000-43-0]
SKU:QM-0144260-01
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Product Details
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Description
MK-8033 hydrochloride is an orally active ATP competitive c-Met/Ron dual inhibitor (IC50s: 1 nM (c-Met),7 nM (Ron) ), with preferential binding to the activated kinase conformation. MK-8033 hydrochloride can be used in the research of cancers, such as breast and bladder cancers, non-small cell lung cancers (NSCLCs) [1][2].
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CAS Number
[1283000-43-0]
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Molecular Formula
C25H22ClN5O3S
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Molecular Weight
507.99
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Smiles
O=S(CC1=CC=C2C(C(C3=CC(C4=CN(C)N=C4)=CN=C3C=C2)=O)=C1)(NCC5=NC=CC=C5)=O.Cl
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Target
C-Met/HGFR
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Concentration
10mM
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Purity
99.86
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Solubility
DMSO : 5.88 mg/mL (ultrasonic) |H2O : 7.14 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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MK-8033 (hydrochloride) [CAS 1283000-43-0]
MK-8033 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.