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MK-8353 (hydrochloride) [CAS 1951448-73-9]

MK-8353 (hydrochloride) [CAS 1951448-73-9]

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SKU:QM-0003674

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  • Description

    MK-8353 (SCH900353) hydrochloride is a potent, selective, orally active ERK1/2 inhibitor with IC50 values of 23.0 nM and 8.8 nM, respectively. MK-8353 exhibits antitumor activity[1].

  • CAS Number

    [1951448-73-9]

  • Molecular Formula

    C37H42ClN9O3S

  • Molecular Weight

    728.31

  • Smiles

    O=C([C@@]1(SC)CN(CC(N2CC=C(C3=CC=C(C4=NN(C)C=N4)C=C3)CC2)=O)CC1)NC5=CC6=C(NN=C6C7=CC=C(OC(C)C)N=C7)C=C5.Cl

  • Target

    ERK

  • Isoform

    ERK1; ERK2

  • Shipping Conditions

    Room temperature

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MK-8353 (hydrochloride) [CAS 1951448-73-9]

MK-8353 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.