Modakafusp alfa [CAS 2254522-19-3]
Modakafusp alfa [CAS 2254522-19-3]
SKU:QM-0197968-01
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Product Details
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Description
Modakafusp alfa (TAK-573) is a humanized, anti-CD38 IgG4 monoclonal antibody fused to 2 attenuated IFNα2b molecules, which delivers interferon-alpha to CD38-expressing cells. Modakafusp alfa has direct anti-proliferative activity on multiple myeloma (MM) cancer cells in vitro and induces robust and durable antitumor responses in MM xenograft tumor models. Modakafusp alfa in combination with anti-PD-1 antibodies induces immunomodulation and antitumor responses with good tolerance in mice[1][2][3][4].
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CAS Number
[2254522-19-3]
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Smiles
[Modakafuspalfa]
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Target
CD38
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Purity
96.22
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Solubility
10 mM in DMSO
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Storage Conditions
Store at -80°C for 2 years
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Shipping Conditions
Dry Ice
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Modakafusp alfa [CAS 2254522-19-3]
Modakafusp alfa is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.