Molidustat [CAS 1154028-82-6]
Molidustat [CAS 1154028-82-6]
SKU:QM-0141970-01
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Product Details
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Description
Molidustat (BAY 85-3934) is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with IC50 values of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD3, respectively. Molidustat can elevate the levels of circulating erythropoietin (EPO) to near-normal physiological ranges. Molidustat can be utilized in the research of renal anemia[1][2].
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CAS Number
[1154028-82-6]
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Molecular Formula
C13H14N8O2
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Molecular Weight
314.3
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Smiles
O=C1C(N2N=NC=C2)=CNN1C3=NC=NC(N4CCOCC4)=C3
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Target
HIF/HIF Prolyl-Hydroxylase
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Purity
99.7
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Solubility
DMSO : 5 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H360, H372
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Precautions
H302, H360, H372
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Molidustat [CAS 1154028-82-6]
Molidustat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.