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Momelotinib-d4 (dihydrochloride hydrate) [CAS 2056097-81-3]
Momelotinib-d4 (dihydrochloride hydrate) [CAS 2056097-81-3]
SKU:QM-0003563
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Product Details
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Description
Momelotinib-d4 (CYT387-d4) dihydrochloride hydrate is a deuterium labeled Momelotinib. Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50s of 11 nM and 18 nM, respectively. CYT387 shows much less activity against JAK3[1].
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CAS Number
[2056097-81-3]
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Molecular Formula
C23H22D4Cl2N6O3
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Molecular Weight
509.42
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Smiles
N#CCNC(C(C=C1)=CC=C1C2=NC(NC3=CC=C(N4C([2H])([2H])COCC4([2H])[2H])C=C3)=NC=C2)=O.Cl.O.Cl
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Target
Apoptosis; Autophagy; Isotope-Labeled Compounds; JAK
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Shipping Conditions
Room temperature
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Momelotinib-d4 (dihydrochloride hydrate) [CAS 2056097-81-3]
Momelotinib-d4 (dihydrochloride hydrate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.