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Momelotinib (mesylate) [CAS 1056636-07-7]
Momelotinib (mesylate) [CAS 1056636-07-7]
SKU:QM-0000288
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Product Details
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Description
Momelotinib mesylate (CYT387 mesylate) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, appr 10-fold selectivity versus JAK3.
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CAS Number
[1056636-07-7]
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Molecular Formula
C24H26N6O5S
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Molecular Weight
510.57
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Smiles
O=C(C1=CC=C(C2=NC(NC3=CC=C(N4CCOCC4)C=C3)=NC=C2)C=C1)NCC#N.O=S(O)(C)=O
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Target
Autophagy; JAK
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Isoform
JAK1; JAK2; JAK3
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Momelotinib (mesylate) [CAS 1056636-07-7]
Momelotinib (mesylate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.