Monepantel [CAS 887148-69-8]
Monepantel [CAS 887148-69-8]
SKU:QM-0149445-01
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Product Details
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Description
Monepantel (AAD1566, NUZ-001), an antiparasitic agent, is an orally active mTOR inhibitor. Monepantel triggers autophagy through the deactivation of mTOR/p70S6K signalling pathway. Monepantel is a positive allosteric modulator of a nematode-specific clade of nAChR subunits. Monepantel can be used for the study of amyotrophic lateral sclerosis (ALS) and ovarian cancer[1][2][3][4].
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CAS Number
[887148-69-8]
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Molecular Formula
C20H13F6N3O2S
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Molecular Weight
473.39
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Smiles
O=C(N[C@@](C)(C#N)COC1=CC(C#N)=CC=C1C(F)(F)F)C2=CC=C(SC(F)(F)F)C=C2
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Target
Autophagy; mTOR; nAChR; Parasite
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Concentration
10mM
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Purity
99.98
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Solubility
DMSO : ≥ 100 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Monepantel [CAS 887148-69-8]
Monepantel is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.