Mono (2-ethyl-5-hydroxyhexyl) terephthalate [CAS 1684398-38-6]
Mono (2-ethyl-5-hydroxyhexyl) terephthalate [CAS 1684398-38-6]
SKU:QM-0052297
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Product Details
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Description
Mono (2-ethyl-5-hydroxyhexyl) terephthalate (MEHHTP), a hydroxyl metabolite of the phthalate alternative Di-2-ethylhexyl terephthalate (DEHTP), is a liver X receptor α (LXRα) agonist with a binding energy of -7.41 kcal/mol. Mono (2-ethyl-5-hydroxyhexyl) terephthalate upregulates LXRα downstream targets such as SREBP-1c and FASN and increases lipogenic enzyme activity in hepatocytes, and elevating triglyceride (TG) levels. Mono (2-ethyl-5-hydroxyhexyl) terephthalate is promising for research of nonalcoholic fatty liver disease (NAFLD) [1].
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CAS Number
[1684398-38-6]
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Molecular Formula
C16H22O5
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Molecular Weight
294.34
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Smiles
O=C(C1=CC=C(C(O)=O)C=C1)OCC(CC)CCC(O)C
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Target
Drug Metabolite
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Purity
98.27
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Storage Conditions
Store at room temperature 3 years
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Mono (2-ethyl-5-hydroxyhexyl) terephthalate [CAS 1684398-38-6]
Mono (2-ethyl-5-hydroxyhexyl) terephthalate is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.