MPP+ (iodide) [CAS 36913-39-0]
MPP+ (iodide) [CAS 36913-39-0]
SKU:QM-0204914-01
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Product Details
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Description
MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT) [1][2].
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CAS Number
[36913-39-0]
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Molecular Formula
C12H12IN
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Molecular Weight
297.14
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Smiles
C[N+]1=CC=C(C2=CC=CC=C2)C=C1.[I-]
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Target
Mitochondrial Metabolism
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Purity
99.94
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Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H301+H311+H331, H315, H319, H335
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Precautions
H301+H311+H331, H315, H319, H335
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MPP+ (iodide) [CAS 36913-39-0]
MPP+ (iodide) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.