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MRT67307 (hydrochloride) [CAS 2095432-39-4]
MRT67307 (hydrochloride) [CAS 2095432-39-4]
SKU:QM-0061385
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Product Details
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Description
MRT67307 hydrochloride is a dual inhibitor of the IKKε and TBK-1 with IC50s of 160 and 19 nM, respectively[1]. MRT67307 hydrochloride also inhibits ULK1 and ULK2 with IC50s of 45 and 38 nM, respectively. MRT67307 hydrochloride also blocks autophagy in cells[2].
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CAS Number
[2095432-39-4]
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Molecular Formula
C26H37ClN6O2
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Molecular Weight
501.06
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Smiles
O=C(C1CCC1)NCCCNC2=NC(NC3=CC=CC(CN4CCOCC4)=C3)=NC=C2C5CC5.[H]Cl
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Target
Autophagy; IKK; ULK
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Isoform
IKKε; TBK1; ULK1; ULK2
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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MRT67307 (hydrochloride) [CAS 2095432-39-4]
MRT67307 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.