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MW-150 hydrochloride [CAS 1923773-01-6]
MW-150 hydrochloride [CAS 1923773-01-6]
SKU:QM-0059780
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Product Details
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Description
MW-150 hydrochloride (MW01-18-150SRM hydrochloride) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. MW-150 hydrochloride (MW01-18-150SRM hydrochloride) inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia[1].
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CAS Number
[1923773-01-6]
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Molecular Formula
C24H24ClN5
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Molecular Weight
417.93
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Smiles
CN1CCN(C2=NN=C(C3=CC=C4C=CC=CC4=C3)C(C5=CC=NC=C5)=C2)CC1.[H]Cl
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Target
Autophagy; p38 MAPK
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Isoform
P38α
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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MW-150 hydrochloride [CAS 1923773-01-6]
MW-150 hydrochloride is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.