N- (4-acetamidophenyl) -Indomethacin amide [CAS 261766-23-8]
N- (4-acetamidophenyl) -Indomethacin amide [CAS 261766-23-8]
SKU:QM-0134719-01
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Product Details
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Description
N- (4-acetamidophenyl) -indomethacin amide (N-4-AIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.1 N-4-AIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.12 and 0.625 μM, respectively. It is about 400 times less potent as an inhibitor of human recombinant COX-1 and 80 times less potent as an inhibitor of ovine COX-1 than ovine COX-2.
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CAS Number
[261766-23-8]
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Molecular Formula
C27H24ClN3O4
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Molecular Weight
489.95
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Smiles
O=C(NC1=CC=C(NC(C)=O)C=C1)CC2=C(C)N(C(C3=CC=C(Cl)C=C3)=O)C4=C2C=C(OC)C=C4
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Target
COX
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Shipping Conditions
Room temperature
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N- (4-acetamidophenyl) -Indomethacin amide [CAS 261766-23-8]
N- (4-acetamidophenyl) -Indomethacin amide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.