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N-Deacetylthiocolchicine [CAS 2731-16-0]

N-Deacetylthiocolchicine [CAS 2731-16-0]

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QM-0049518

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Product Details

  • Description

    N-Deacetylthiocolchicine is a tubulin inhibitor with an IC50 value of 2.2 nM in MDR-negative MDA-MB 231 breast cancer cells. N-Deacetylthiocolchicine exerts antiproliferative activity by binding to tubulin to interfere with microtubule assembly, arresting cells in mitosis during the cell cycle. N-Deacetylthiocolchicine is promising for research of malignancies such as breast cancer[1][2].

  • CAS Number

    [2731-16-0]

  • Molecular Formula

    C20H23NO4S

  • Molecular Weight

    373.47

  • Smiles

    COC1=C(C(C([C@@H](N)CC2)=C3)=CC=C(SC)C3=O)C2=CC(OC)=C1OC

  • Target

    Microtubule/Tubulin

  • Shipping Conditions

    Room temperature

  • Hazard Statement

    H302-H315-H319-H335

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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1 EachQM-0049518
1 EachQM-0049518
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N-Deacetylthiocolchicine [CAS 2731-16-0]

N-Deacetylthiocolchicine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.