N-Desethyl Sunitinib (hydrochloride) (Standard)
N-Desethyl Sunitinib (hydrochloride) (Standard)
SKU:QM-0006653
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Product Details
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Description
Glycochenodeoxycholic acid sodium salt (Standard) is the analytical standard of Glycochenodeoxycholic acid sodium salt. This product is intended for research and analytical applications. Glycochenodeoxycholic acid sodium salt (Sodium glycochenodeoxycholate) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid sodium salt inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid sodium salt induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC) . Glycochenodeoxycholic acid sodium salt is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC) [1][2][3][4].
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Molecular Formula
C20H24ClFN4O2
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Molecular Weight
406.88
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Smiles
O=C1NC2=CC=C(F)C=C2/C1=C/C3=C(C)C(C(NCCNCC)=O)=C(C)N3.[H]Cl
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Target
Drug Metabolite; Reference Standards
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Shipping Conditions
Room temperature
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N-Desethyl Sunitinib (hydrochloride) (Standard)
N-Desethyl Sunitinib (hydrochloride) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.