N-Desmethyltamoxifen (hydrochloride) (Standard) [CAS 15917-65-4]
N-Desmethyltamoxifen (hydrochloride) (Standard) [CAS 15917-65-4]
SKU:QM-0005524-01
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Product Details
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Description
N-Desmethyltamoxifen (hydrochloride) (Standard) is the analytical standard of N-Desmethyltamoxifen (hydrochloride) . This product is intended for research and analytical applications. N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation[1][2][3].
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CAS Number
[15917-65-4]
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Molecular Formula
C25H28ClNO
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Molecular Weight
393.95
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Smiles
CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCNC)C=C2)\C3=CC=CC=C3.[H]Cl
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Target
Drug Metabolite; Endogenous Metabolite; Estrogen Receptor/ERR; PKC; Reference Standards
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Shipping Conditions
Room temperature
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Hazard Statement
H350-H360-H400-H410
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Precautions
P273-P280-P391-P405-P501
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N-Desmethyltamoxifen (hydrochloride) (Standard) [CAS 15917-65-4]
N-Desmethyltamoxifen (hydrochloride) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.