N, N, O-Tridesmethylvenlafaxine (Standard) [CAS 149289-29-2]
N, N, O-Tridesmethylvenlafaxine (Standard) [CAS 149289-29-2]
SKU:QM-0049261
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Product Details
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Description
Vardenafil (dihydrochloride) (Standard) is the analytical standard of Vardenafil (dihydrochloride) . This product is intended for research and analytical applications. Vardenafil dihydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil dihydrochloride shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM respectively, while IC50s are >1000 nM for PDE3 and PDE4. Vardenafil dihydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil dihydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes[1]-[6].
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CAS Number
[149289-29-2]
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Molecular Formula
C14H21NO2
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Molecular Weight
235.33
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Smiles
OC1=CC=C(C(C2(O)CCCCC2)CN)C=C1
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Target
Drug Metabolite; Endogenous Metabolite; Reference Standards
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Shipping Conditions
Room temperature
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N, N, O-Tridesmethylvenlafaxine (Standard) [CAS 149289-29-2]
N, N, O-Tridesmethylvenlafaxine (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.