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N3-C4-NHS ester [CAS 478801-48-8]
N3-C4-NHS ester [CAS 478801-48-8]
SKU:QM-0141958-01
£301.50 GBP
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Product Details
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Description
N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-C4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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CAS Number
[478801-48-8]
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Molecular Formula
C9H12N4O4
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Molecular Weight
240.22
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Smiles
O=C(ON1C(CCC1=O)=O)CCCCN=[N+]=[N-]
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Target
ADC Linker
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Isoform
Non-cleavable Linker
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Purity
99.53
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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N3-C4-NHS ester [CAS 478801-48-8]
N3-C4-NHS ester is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.